Neural Matrix: a flexible, multiplexed electrode array for high resolution, long-term recording across species. (A) The 1,008-channel Neural Matrix array. (B) Comparison between the array and other electrodes. (C) Schematic highlighting key encapsulating layers – including an ultrathin layer of thermally-grown silicon dioxide – that enable long-term viability in brain tissue. (D) Schematic circuit diagram of a single unit cell with components for local signal amplification, multiplexing, and active shielding (left). Cross section of transistor with capacitive input from adjacent tissue through the thermal silicon dioxide layer (right).